The course is targeted for an audience of 5-20 young scientists (advanced graduate students, early postdocs). They should have previous basic knowledge on evolutionary biology. The course will not be heavily mathematical but occasionally there will be some formal analyses. However the mathematical knowledge required should be standard for any graduate student of related areas to evolutionary biology.
Consequently, there no special pre-requisite for this course. We will make a direct jump into how to understand the origin and evolution of complex organism -or parts of them.
This course is a complement to basic curricula of Evolutionary Biology and should be considered as an advanced course.
The attendants should be at least familiar with the notions of selection, evolution cell biology and domains of life. Knowledge of math and chemistry is useful but not mandatory.
Most of the course is conceptual in the sense that it will be based on classroom discussions. However, several "field trips" (not really: rounds in the museum) will complement and enhance the knowledge and experience.
By the end of the course, students and attendants should have learnt:
There will be quite some reading.
There will be four methods of evaluation:
You should not worry about grades but about learning.
|May 4th, 2016||11:00-12:00||Seminal lecture "The Major Transitions in Evolution" by Eörs Szathmáry|
|May 11th, 2016||16:45-18:15||Origin of metabolism|
|May 18th, 2016||16:45-18:15||Emergence of protocells|
|18:30-20:00||Origin of the genetic code|
|May 25th, 2016||16:45-18:15||Origin of chromosomes|
|18:30-20:00||Origin of sex and syngamy (taught with Nick Barton)|
|June 1st, 2016||16:45-18:15||Eukariotic cell + field trip|
|June 8th, 2016||16:45-18:15||Eusociality + field trip|
|18:30-20:00||Origin of language (taught with Eörs Szathmáry)|
|June 15th, 2016||16:45-20:00||Group activities and individual evaluation|
|Read: Maynard Smith & Szathmáry (1995) Ch. 1 AND Szathmáry and Maynard Smith (1995)||May 4|
|Read: Szathmáry, E. (2015). Toward major evolutionary transitions theory 2.0. PNAS 112(33), 10104–10111.||May 11|
|Read: Maynard Smith & Szathmáry (1995) Chs. 3 AND 4||May 11|
|Read: Maynard Smith & Szathmáry (1995) Chs. 5 - 7||May 18|
|Hand In: Summary sheets for "Origin of Metabolism" and "First Replicators"||May 18|
|Read: Maynard Smith & Szathmáry (1995) Chs. 7, 9-10||May 25|
|Hand In: Summary sheet for "Origin of the genetic code"||May 25|
|Read: Maynard Smith & Szathmáry (1995) Ch. 8, and selected sections of Chs. 12, 11, 15 (see below)||June 1|
|Hand In: Summary sheet for "Protocells" and "Origins of Sex"||June 1|
|Hand In: Summary sheet for "Eukaryotic Cell" and "Multicellularity"||June 8|
|Hand In: Review of the Projection "Origins of Life"||June 8|
|Hand In: Summary sheet for "Eusociality" and "Origin of Language"||June 15|
Central reading from
[MS&S95] Maynard Smith, J. & Szathmáry, E., (1995). The Major Transitions in Evolution. Oxford. 346 pp.
Literature to read before the sessions (the list will gradually grow):